P2408 - Scientist/Senior Scientist Oncology, Translational Pharmacology

Debiopharm is privately-owned Swiss biopharmaceutical company committed to research in oncology and infectious diseases in order to improve patient outcomes and quality of life.

Debiopharm International SA aims to develop innovative therapies via our unique development only business model, acting as a bridge between disruptive discovery products and patient access in international markets.

At Debiopharm you will be at the forefront of the fight against cancer and infectious diseases through working on innovative medicines for patients.

Join our team at Debiopharm where together, we innovate, we impact, and we grow.

For our Translational Medicine organization based at our Headquarters in Lausanne, we are looking for a

Scientist / Senior Scientist Oncology, Translational Pharmacology Unit

In this role, you will represent the Translational Pharmacology function in Translational Medicine team and participate in the development of new innovative medicines in oncology.

The mission of the Translational Pharmacology unit is to understand how drugs work to guide and accelerate drug development.

At Debiopharm you will be at the forefront of the fight against cancer, and you will have the opportunity to work on a large range of new innovative medicines for patients.

Your responsibilities will be but not limited to :

• Design, plan, manage and report primary and secondary pharmacology studies performed in Contract Research Organizations :
• In vitro / in vivo pharmacology compounds selection and profiling, including off-target characterization
• Proof of concept in vivo studies PK / PD
• Mechanism of action studies
• Propose innovative solutions to develop new compounds
• Identify the intellectual property, inventions and innovation opportunities, and collaborate with legal department to feed DPI’s patent portfolio
• Identify and develop the clinical pharmacodynamic biomarkers assays to be implemented in clinical studies.
• Participate in the preparation of the pharmacology documentation for health authorities (e.g investigator drug brochures, informed consent forms, lab manuals, clinical protocols and reports)
• Participate in internal and external scientific communications
• Participate in due diligence and contribute to in / out licensing activities

Requirements

• PhD in the field of biomedical research, biomedical engineering or equivalent
• At least 5-year experience in antibody discovery & development in oncology in pharma or biotech
• Experience with in silico and / or in vitro and / or in vivo experimental approaches to characterize antibody mode of action
• Experience in antibody-drug conjugated and / or bi-specific antibody development
• Knowledge of animal welfare regulations
• Experience in bioinformatics is a plus
• Experience in selection and management of Contract Research Organizations
• Excellent communication skills (oral and written) in English
• You are solution-oriented, resilient to push forward the R&D projects and look to work on complex and innovative compounds, willing to be hands-on in activities
• You have excellent commend of data analysis and visualization tools and have good IT skills
• You are used in working in cross-functional team and fast-paced environment and are a team player, looking to tackle challenges together with your team
• You are curious and you propose innovative solutions

Benefits

Debiopharm offers employees :

• International, highly dynamic environment with a long-term vision.
• Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry
• Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry
• Participation in a company where innovation, people and entrepreneurship are the fundamental keys to success.
• Proud to be an Equal-Pay certified, we ensure offering to all our employees the same opportunities

The use of external staffing agencies or recruiters requires prior approval from our Human Resources Department. The Human Resources Department at Debiopharm requests external staffing agencies or recruiters not to contact Debiopharm employees or members of the Board of Directors directly in an attempt to present candidates.

Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.

Debiopharm will not accept unsolicited resumes from any source other than candidates themselves for either current or future positions.