Research Assistant/Lab Technician Position in Blood Cancer Biology and Immunotherapy

Your position

The successful candidate will support the research group and individual scientists with lab maintenance,experimental work, and biobanking.

Your responsibilities will include:

• Laboratory maintenance
• Preparation of common lab reagents
• Biobanking of human blood and bone marrow samples including documentation
• Technical support of PhD students and postdocs, including with cell culture and animal experiments

Experimental approaches in our group include in vivo leukemia and allogeneic hematopoietic stem celltransplantation models, liquid chromatography-mass spectrometry metabolomics and lipidomics, functionalgenomics and CRISPR screens, spectral flow cytometry, cell sorting, bulk, single-cell and spatialtranscriptomics, and functional immune and metabolic assays. The successful candidate will have theopportunity to learn and independently apply several of these techniques.
Research environment
The Apostolova Lab is based at the Department of Biomedicine, University of Basel, in a highly interactiveenvironment spanning cancer biology, immunology, genomics, metabolism, and translational medicine. Ourgroup combines mechanistic leukemia models with metabolism, immunology, and multi-omics to understandhow leukemia cells adapt to therapeutic pressure and interact with the immune system. The successful candidate will have the opportunity to join a young and dynamic group conducting high-levelresearch in hematology. The candidate will receive direct support from the lab manager and other scientists toset their mark in the lab and will be actively involved in the lab projects, providing multiple opportunities fortraining in flow cytometry, molecular biology, metabolism assays, and in vivo experimentation. Mentorship andrespect for human values, including diversity, equity, and inclusiveness, are driving forces of our group.

Your profile

• Training as a molecular biology research technician (lab technician) or M.Sc. (or equivalent) in biological sciences or related fields
• Proficient in basic lab techniques (cell culture, working in sterile conditions, PCR)
• Previous experience with processing human blood samples, animal work, molecular biology, flow cytometry, or metabolism assays will be advantageous
• Willingness to work with animal models
• Interest in hematology, tumor immunology, and metabolism
• Excellent communication skills (English mandatory, German advantageous) and the ability to work collaboratively in an interdisciplinary team