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Research Associate, Mitochondrial Therapy Translational Research

The Biozentrum, University of BaselBasel, CH

Design and execute genome-wide CRISPR knockout, CRISPRa, and CRISPRi screens in mammalian cell models.Validate screening hits using arrayed CRISPR experiments and orthogonal func-tional assays in r... Mehr anzeigen

Facility Associate & Deputy Facility Coordinator (m/w/d)

Oettinger Davidoff AGBasel, CH

Die Oettinger Davidoff Gruppe mit einem Umsatz von über einer halben Milliarde Schweizer Franken und über 4'000 Beschäftigten auf der ganzen Welt kann ihre Wurzeln bis ins Jahr 1875 zurückführen un... Mehr anzeigen

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Cloud Platform Engineer

Friedrich Miescher Institute for Biomedical ResearchBasel, CH

The IT team of the Friedrich Miescher Institute for Biomedical Research (FMI) is looking for an experienced .FMI’s transition to a modern hybrid cloud architecture.The FMI IT team supports 20 scien... Mehr anzeigen

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PostDoc, Computational and Experimental Approaches to Visual Physiology

The Biozentrum, University of BaselBasel, CH

Own the computational and experimental approaches to study the physiology of vision.Define clear research questions to advance our understanding of retinal pathophysiology, natural vision, and info... Mehr anzeigen

Principal - Global Custom Integrated Research

IQVIABasel, Switzerland

We’re passionate about improving the life sciences ecosystem and making decisions that accelerate innovation for a healthier world.Every day our team develops evidence-based strategies that are use... Mehr anzeigen

Post-Doctoral Research Position in Digital & Computational Toxicology

The Biozentrum, University of BaselBasel, CH

Develop and implement FAIR-compliant data management strategies, standards and data management plans.Build, curate and maintain toxicological datasets and digital knowledge resources from public da... Mehr anzeigen

Lab Associate – Cellular, Functional & Soluble Biomarkers (m/w/d) (LSW) – Basel

Manpower SwitzerlandBasel

MANPOWER AG – Ihre Karriere im Fokus!.Mit unseren drei Marken – Manpower, Experis und Talent Solutions – unterstützen wir Unternehmen verschiedenster Branchen bei der Personalbeschaffung.Seit 75 Ja... Mehr anzeigen

Research Associate (In Vivo) (m/f/d)

HaysBasel Stadt

Freelance/Contracting project Basel Stadt Start date: asap Reference number: 865654/1.Diesen Job teilen oder drucken.Design, conduct, and analyze in vivo studies involving intravenous injections, b... Mehr anzeigen

Interaction Analytics (Level: Senior Research Associate to Scientist)

Ridgeline DiscoveryBasel, Basel-Stadt, CH

Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe.In recent year... Mehr anzeigen

Associate Analytical Expert

SobiBasel, Basel-Stadt, Switzerland

Join Sobi’s Global CMC Science & Technology team and help shape how our medicines are developed and supplied worldwide.Sobi products by coordination of the stock of Critical Analytical Material... Mehr anzeigen

(Associate) Director, CMC Analytical Development

RhyGaze AGBasel, Basel City, Switzerland
Quick Apply

RhyGaze is a biotech company developing transformative gene therapies to restore vision in patients with blindness.Our programs target patients with blinding retinal diseases, and we are committed ... Mehr anzeigen

Associate Partner - AI & Data - Life Sciences

Visium SABasel, BS, CH
Quick Apply

Visium combines strategy, frontier AI, and deep regulated-industry expertise to build and deploy AI-native systems that reinvent how businesses operate - unlocking the value of AI at scale.We're no... Mehr anzeigen

Audit Associate 80-100%

AdeccoBasel, Bs, Switzerland

Für unseren Kunden, ein etabliertes Prüfungs‑ und Beratungsunternehmen, suchen wir eine engagierte Persönlichkeit als Audit Associate 80-100%.In dieser Rolle wirkst du aktiv bei Prüfungsmandaten mi... Mehr anzeigen

Associate Director, Commercial Training, Europe

BeiGeneBasel

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals.When considering candidates, we look for scientific and business professionals who ... Mehr anzeigen

Azure Engineer

MDigital AGMuttenz, Basel-Landschaft, Switzerland
Quick Apply

Du willst nicht einfach ein paar Ressourcen in Azure anklicken.Du willst echte Kundenumgebungen modernisieren, Migrationen umsetzen und Verantwortung übernehmen.Dann könnte das hier zu Dir passen.W... Mehr anzeigen

German Speaking Jr Sales & Marketing Consultant in Barcelona w/Relocation Bonus

Cross Border TalentsBasel, Switzerland
Quick Apply

We are seeking a dynamic and driven German-speaking Marketing & Sales Assistant to join our team in Barcelona.This role offers a relocation bonus to help you make a smooth transition.Included f... Mehr anzeigen

Associate Director, Commercial Insights and Analytics

BeiGeneBasel

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals.When considering candidates, we look for scientific and business professionals who ... Mehr anzeigen

Global Medical Director Gastroenterology

AbbottBasel, Basel-City, Switzerland

Global Medical Director – Gastroenterology.Abbott | Established Pharmaceutical Division.As a global healthcare leader with more than.LATAM, APAC, India, and Emerging Markets.Our diverse portfolio s... Mehr anzeigen

Senior Business Partner Executive Search (a)

NWS Management AGBasel, CH

Als Executive Search Boutique begleiten wir Schweizer Unternehmen bei der Gewinnung von Führungspersönlichkeiten fokussiert, effizient, diskret.Zur Erweiterung unserer Präsenz suchen wir Senior Bu... Mehr anzeigen

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Research Associate, Mitochondrial Therapy Translational Research

Research Associate, Mitochondrial Therapy Translational Research

The Biozentrum, University of BaselBasel, CH
Vor 12 Tagen
Stellenbeschreibung

Your position

  • Design and execute genome-wide CRISPR knockout, CRISPRa, and CRISPRi screens in mammalian cell models
  • Validate screening hits using arrayed CRISPR experiments and orthogonal func-tional assays in relevant disease models
  • Establish, optimize, and routinely perform cell-line generation workflows using mito-chondrial transfer in immortalized and primary cells
  • Generate and analyze NGS and RNA-seq data from primary tissues and cultured cells
  • Develop and optimize cell-type-targeted mitochondrial transfer approaches in rele-vant in vitro and ex vivo models
  • Independently design, perform, document, and interpret experiments in a rigorous and reproducible manner
  • Work closely with technical staff and help supervise research assistants while re-maining experimentally active
  • Contribute experimentally to translational documentation, regulatory preparation, and clinical protocol development
  • Present experimental results internally, to collaborators, and at international confer-ences
  • Mentor junior lab members through direct experimental guidance and training

Your profile

  • PhD in biology, cell biology, molecular medicine, or a related field
  • Strong hands-on experience with CRISPR-based screening and NGS analysis
  • Solid background in cell culture, molecular biology, and in vitro functional assays
  • Experience with recombinant protein production
  • Experience with RNA sequencing is desirable
  • Demonstrated ability to work independently and manage large-scale, multi-step ex-periments
  • Experience working under BSL-2 conditions
  • Excellent organizational skills and strong attention to experimental detail
  • Clear scientific communication skills and a collaborative working style