PhD position on cartilage and osteochondral bioprinting for joint restoration

Your position

The project aims to develop cartilage and osteochondral using nasal chondrocytes (cells in clinical use for repairing cartilage defects) and Melt electrowriting (MEW, i.

e., an approach that combines electrospinning with 3D printing). In particular, the effect of scaffold architecture on nasal chondrocyte differentiation will be assessed.

Additionally, the project aims to evaluate the regenerative capacity of the manufactured grafts in vivo (i.e., temporomandibular joint defect model in animals).

The candidate is expected to :

• CAD Design, material optimization, and MEW scaffold printing
• Design and conduct in vitro experiments,
• Explore the maturation of the grafts in vitro
• Generate the grafts for the animal study and analyze the regenerative tissues
• Generate scientific texts, including abstracts, publications, presentations, and protocols
• Supervision and teaching of BME / medical students

Your profile

We seek a highly motivated candidate with :

• MSc in Biomedical Engineering, Material science, biotechnology, or biology or similar (required)
• Background in musculoskeletal research, cell and molecular biology, biochemistry, or tissue engineering (strong advantage)
• Experience with Biomaterial, Bioprinting and Melt Electrowriting printing (Hydrogel, Polymers, mechanical test characterization)
• Experience with cell and tissue culture, qPCR, immunoassays, viability assays, microscopy, or histology (strong advantage)
• Excitement to work in a collaborative, interdisciplinary environment
• Independent thinking, ambition, focus on discovery, and dedication to perform research of the highest quality
• Excellent communication and writing skills (English)
5 giorni fa