PhD position on "On-Chip Separation of Proteins for Single-Cell Proteome Profiling"

Institute for Biomedical Engineering (D-ITET)
Zurich
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Job description

  • You will be developing a platform for the detection of protein production and secretion in single cells. An example of application is to study antibody secretion in immune cells upon their activation
  • You will be optimizing recently established scanning nanopore microscope for specific detection of proteins in complex physiological solutions, addressing these open research challenges :
  • Specificity of the sensor towards selected proteins : Enhancing the contrast for specific proteins
  • Data analysis : Improving data analysis approaches for capturing more information from each individual protein
  • Sampling from single cells : Developing methods for better sampling from individual cells, and handling of small volume samples
  • You will be collaborating with colleagues from the machine learning domain to improve data analysis
  • You will be responsible for project meetings, reporting, scientific publications, and conference / seminar presentations
  • You will supervise master / bachelor students

Profile

Successful candidates should have

  • Solid working knowledge in either on-chip protein separation, microfluidics or nanofluidic.
  • Hands-on experience with protein samples.
  • Working experience in cell labs is valuable.
  • Familiarity with data analysis using bioinformatic tools is highly valuable.
  • Independent personality, self-driven, creative, solution-oriented, open-minded, team-player & collaborative.

Workplace

Workplace

We offer

Il y a plus de 30 jours
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