(Senior) Toxicology Expert& Biologics / Project in Immunology

GRANITE BIO is seeking a (Senior) Toxicology Expert, Biologics / Project in Immunology .

GRANITE BIO is a recently established biotechnology company in the Ridgeline Discovery incubator located in Basel (Switzerland).

Based on fundamental research over the last two decades, GRANITE BIO’s differentiated approach is to impact central disease biology nodes to transform inflammatory, autoimmune and fibrotic conditions.

The lead therapeutic antibody received clinical trial approval by competent health authorities to initiate Ph1(b) trial in Q1 / 2024.

We are seeking a highly motivated and experienced Toxicologist Expert to join our team. The successful candidate will play a critical role in advancing our biologics projects in immunology from preclinical to clinical stages.

RESPONSIBILITIES

• Plan and execute (chronic) toxicology studies non-human primates to support Ph2 clinical development of our biologics projects in immunology after both IV and SC administrations.
• Develop a tailored toxicology strategy for pre-clinical programs to enable IND / CTA and later clinical development until launch including special cases such as in vitro-only safety testing strategies.
• Interpret and integrate in vitro and in vivo data from immuno safety and toxicology studies and provide expert advice to project teams
• Collaborate with cross-functional teams to ensure the successful progression of projects from discovery through to clinical development.
• Prepare and review regulatory documents and responses to regulatory authorities taking the lead in all Toxicology-related aspects.
• Stay current with new developments in toxicology and immunology and apply this knowledge to the design of toxicology and immune safety studies.

WHO YOU ARE

• PhD in Toxicology, Pharmacology, Immunology, or related field.
• Minimum of 5 years of experience in the biotech / pharmaceutical industry, with a focus on biologics and immunology.
• Proven track record in designing and executing in vitro an in vivo immune safety and toxicology studies.
• Strong knowledge of immunology and experience in the development of biologics.
• Excellent communication and collaboration skills.

WHAT WE CURRENTLY OFFER

• Offices : Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.
• Commuter Benefits : We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
• Flexible Working : We support flexible working as appropriate.
• Christmas Closure : In addition to the 24 holidays per year, our offices / labs are closed between Christmas and New Year.
• Birthday Retreat : On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
• Food : We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
• Coffee : Meet up with your colleagues and grab free coffee.
• Development : We support the individual development of our employees.
• Creativity : We offer an innovative and creative environment.
• People : We are an international and diverse team with talented and passionate people.
• Fun : From time-to-time we organise cool off-site summer and winter team events.

To apply, please send us this application form together with your CV, Cover Letter and Reference Letters (Arbeitszeugnisse) .