Stellenbeschreibungppb Senior Clinical Pharmacologist /b /p /p Location: p Allschwil, Basel Area, BL, CH /p pThe purpose of Idorsia is to challenge accepted medical paradigms, answering the questions that matter most. To achieve this, we will discover, develop, and commercialize transformative medicines – either with in-house capabilities or together with partners – and evolve Idorsia into a leading biopharmaceutical company, with a strong scientific core. /p pWe are seeking an experienced, entrepreneurial bSenior Clinical Pharmacologist /b to join our organization. In this role, you will operate in a blean, fast-paced environment /b with established core processes and systems, influencing the clinical pharmacology strategy across a bhigh volume of First-in-Human (FIH) and early clinical programs /b, as well as ongoing studies. /p pThis is a hands-on, high-impact role within Global Clinical Development, offering significant visibility and growth potential in the organization, and requiring close collaboration with bTranslational Research. /b /p pbKey Responsibilities /b /p liLead the design and execution of bclinical pharmacology strategies /b and corresponding studies across multiple programs, /li liDevelop innovative and meaningful clinical pharmacology approaches that accelerate and de-risk drug development /li liDefine bdose selection, escalation strategies, and characterize exposure-response relationships /b /li liEnsure integration of bnonclinical, translational, biomarker and clinical data /b to inform development decisions /li liDesign clinical studies with appropriate pharmacokinetic (PK) and pharmacodynamic (PD) endpoints /li liApply biomarkers and model-informed drug development (MIDD) approaches to enhance study design and decision-making /li liAuthor and contribute to protocol development, including statistical and modeling/simulation considerations /li liServe as the primary clinical pharmacology interface with: Research, Translational Sciences, Biostatistics, Regulatory Affairs /li liRepresent clinical pharmacology at life cycle meetings /li liLead scientific discussions and provide strategic input in bprogram governance meetings /b and decision-making forums /li liManage a blarge inflow of new clinical candidates /b alongside ongoing studies /li liAuthor and contribute to regulatory documentation (IND/CTA, briefing documents, health authority responses) /li liRepresent clinical pharmacology in agency interactions as a subject matter expert /li liManage and oversee external partners (CROs, modeling vendors) /li pbQualifications Experience /b /p liPhD, PharmD, MD, or equivalent in Clinical Pharmacology, Pharmacokinetics, or related field /li lib10+ years /b of job relevant industry experience in biotech/pharma /li liProven track record in: Early clinical development (FIH through proof-of-concept) Study design and dose justification PK/PD modeling and interpretation /li liExperience managing bmultiple concurrent programs /b in a dynamic environment /li libEntrepreneurial mindset /b and intellectual curiosity with ability to thrive in ambiguity and rapid change /li liStrong scientific leadership with a bhands-on, execution-oriented approach /b /li liDemonstrated ability to translate clinical pharmacology data into high-quality manuscripts, abstracts, and conference presentations /li liExcellent cross-functional collaboration and influencing skills /li liAbility to balance bstrategic thinking with operational delivery /b /li pbWhy Join Us? /b /p liJoin a science-led organization with a proven track record of innovative medicines from discovery to launch /li liOpportunity to work on bmultiple innovative early-stage programs with a /bhigh level of ownership and visibility across the organization /li libThrive in an agile and entrepreneurial culture /b that champions innovative development over bureaucracy /li pbWork Location: /b Allschwil, Switzerland (primarily on-site) /p pbBusiness Area: /b Global Clinical Development /p pbJob Type: /b Permanent, full time /p pbJob ID /b: 4767 /p pbAt Idorsia, we harness the power of difference, authenticity, and inclusion to achieve business success.br/ We encourage all potential candidates with diverse backgrounds of race, color, religion, sexual orientation, gender identity, age, national origin, and disability to submit their job applications. All applicants will receive consideration.br/ We are committed to fostering respect, fairness, and equal opportunities for all job applicants and our employees. /b /p pPlease be informed that if you are selected for this position, your employment will be subject to a pre-employment background screening process, of which you would be informed in greater detail in due course. /p pIdorsia Pharmaceuticals Ltd ("Idorsia") is committed to a fair and transparent application process. In order to avoid any conflict of interest in line with Idorsia Code of Business Conduct, which would undermine such a commitment, the applicants must disclose any personal, financial, or other outside interests interfering with the interests of Idorsia. Further, the applicant is obliged to disclose any and all relationships with close or affiliated persons, who are employees of Idorsia or are collaborating with Idorsia in any other contractual relationship. /p pPlease note Idorsia operates a strictly controlled list of preferred recruitment partners. For those partners who have no valid, signed Master Service Agreement in place with Idorsia, all unsolicited resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to personal e-mail accounts of employees of Idorsia Pharmaceuticals (including any of its subsidiaries, affiliates, or related companies) are considered the property of Idorsia Pharmaceuticals and are not subject to payment of any form of introduction, placement or referral fees. /p
