Phd candidate Jobs in Basel

Senior Clinical Pharmacologist

Location:

Allschwil, Basel Area, BL, CH

The purpose of Idorsia is to challenge accepted medical paradigms, answering the questions that matter most. To achieve this, we will discover, develop, and commercialize transformative medicines – either with in-house capabilities or together with partners – and evolve Idorsia into a leading biopharmaceutical company, with a strong scientific core.

We are seeking an experienced, entrepreneurial Senior Clinical Pharmacologist to join our organization. In this role, you will operate in a lean, fast-paced environment with established core processes and systems, influencing the clinical pharmacology strategy across a high volume of First-in-Human (FIH) and early clinical programs, as well as ongoing studies.

This is a hands-on, high-impact role within Global Clinical Development, offering significant visibility and growth potential in the organization, and requiring close collaboration with Translational Research.

Key Responsibilities

• Lead the design and execution of clinical pharmacology strategies and corresponding studies across multiple programs,
• Develop innovative and meaningful clinical pharmacology approaches that accelerate and de-risk drug development
• Define dose selection, escalation strategies, and characterize exposure-response relationships
• Ensure integration of nonclinical, translational, biomarker and clinical data to inform development decisions
• Design clinical studies with appropriate pharmacokinetic (PK) and pharmacodynamic (PD) endpoints
• Apply biomarkers and model-informed drug development (MIDD) approaches to enhance study design and decision-making
• Author and contribute to protocol development, including statistical and modeling/simulation considerations
• Serve as the primary clinical pharmacology interface with: Research, Translational Sciences, Biostatistics, Regulatory Affairs
• Represent clinical pharmacology at life cycle meetings
• Lead scientific discussions and provide strategic input in program governance meetings and decision-making forums
• Manage a large inflow of new clinical candidates alongside ongoing studies
• Author and contribute to regulatory documentation (IND/CTA, briefing documents, health authority responses)
• Represent clinical pharmacology in agency interactions as a subject matter expert
• Manage and oversee external partners (CROs, modeling vendors)

Qualifications & Experience

• PhD, PharmD, MD, or equivalent in Clinical Pharmacology, Pharmacokinetics, or related field
• 10+ years of job relevant industry experience in biotech/pharma
• Proven track record in: Early clinical development (FIH through proof-of-concept) Study design and dose justification PK/PD modeling and interpretation
• Experience managing multiple concurrent programs in a dynamic environment
• Entrepreneurial mindset and intellectual curiosity with ability to thrive in ambiguity and rapid change
• Strong scientific leadership with a hands-on, execution-oriented approach
• Demonstrated ability to translate clinical pharmacology data into high-quality manuscripts, abstracts, and conference presentations
• Excellent cross-functional collaboration and influencing skills
• Ability to balance strategic thinking with operational delivery

Why Join Us?

• Join a science-led organization with a proven track record of innovative medicines from discovery to launch
• Opportunity to work on multiple innovative early-stage programs with a high level of ownership and visibility across the organization
• Thrive in an agile and entrepreneurial culture that champions innovative development over bureaucracy

Work Location: Allschwil, Switzerland (primarily on-site)

Business Area: Global Clinical Development

Job Type: Permanent, full time

Job ID: 4767

At Idorsia, we harness the power of difference, authenticity, and inclusion to achieve business success.
We encourage all potential candidates with diverse backgrounds of race, color, religion, sexual orientation, gender identity, age, national origin, and disability to submit their job applications. All applicants will receive consideration.
We are committed to fostering respect, fairness, and equal opportunities for all job applicants and our employees.

Please be informed that if you are selected for this position, your employment will be subject to a pre-employment background screening process, of which you would be informed in greater detail in due course.

Idorsia Pharmaceuticals Ltd ("Idorsia") is committed to a fair and transparent application process. In order to avoid any conflict of interest in line with Idorsia Code of Business Conduct, which would undermine such a commitment, the applicants must disclose any personal, financial, or other outside interests interfering with the interests of Idorsia. Further, the applicant is obliged to disclose any and all relationships with close or affiliated persons, who are employees of Idorsia or are collaborating with Idorsia in any other contractual relationship.

Please note Idorsia operates a strictly controlled list of preferred recruitment partners. For those partners who have no valid, signed Master Service Agreement in place with Idorsia, all unsolicited resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to personal e-mail accounts of employees of Idorsia Pharmaceuticals (including any of its subsidiaries, affiliates, or related companies) are considered the property of Idorsia Pharmaceuticals and are not subject to payment of any form of introduction, placement or referral fees.