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Research Associate, Mitochondrial Therapy Translational Research

The Biozentrum, University of BaselBasel, CH

Design and execute genome-wide CRISPR knockout, CRISPRa, and CRISPRi screens in mammalian cell models.Validate screening hits using arrayed CRISPR experiments and orthogonal func-tional assays in r... Mehr anzeigen

Head of Global Medical Publications

SobiBasel, Basel-Stadt, Switzerland
Homeoffice

Manage, lead, and coach a team of publication managers, fostering a collaborative and high-performance culture.Oversee the planning, development, and execution of strategic publication plans across... Mehr anzeigen

Computational Chemistry / CADD (Level: Principal Scientist to Director)

Ridgeline DiscoveryBasel, Basel-Stadt, CH

Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe.In recent year... Mehr anzeigen

Associate Director, Technical Project Leader Drug Product

IdorsiaBasel, CH

Associate Director, Technical Project Leader Drug Product.The purpose of Idorsia is to discover, develop, and commercialize innovative medicines to help more patients.Headquartered in Switzerland –... Mehr anzeigen

Head of Development - Innovative Synthesis

Corden Pharma Switzerland LLCLiestal, CH

Head of Development (m/f/d) - Innovative Synthesis.CordenPharma is a leading full-service Contract Development and Manufacturing Organization (CDMO) specializing in active pharmaceutical ingredient... Mehr anzeigen

 • Gesponsert

Lab Associate – Cellular, Functional & Soluble Biomarkers (m/w/d) (LSW) – Basel

Manpower SwitzerlandBasel

MANPOWER AG – Ihre Karriere im Fokus!.Mit unseren drei Marken – Manpower, Experis und Talent Solutions – unterstützen wir Unternehmen verschiedenster Branchen bei der Personalbeschaffung.Seit 75 Ja... Mehr anzeigen

 • Gesponsert

Translation Imaging Lead m/f/d

Bayer Consumer Care AGBasel, CH

At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where ,Health for all, Hunger for none' is nolonger a dream, but a real possibility.We're doing ... Mehr anzeigen

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Associate Safety Director

CTCBasel and NW Switzerland, CH

Develop and maintain expert knowledge of product safety profiles, disease contexts, competitor safety data, and mechanisms of action.Lead medical reviews for individual case safety reports (ICSR) a... Mehr anzeigen

Disease Area Head CVRM

Genentech, IncBasel

Our Global Pharma Strategy (GPS) team plays a pivotal role in shaping the future of healthcare by driving the strategic direction of our innovative product portfolio.As a member of the GPS team, yo... Mehr anzeigen

Backend Application Developer (Core Specialist Tier)

AllpsBasel, Basel City, Switzerland
Quick Apply

Backend Application Developer – Core Specialist Tier.Contract Duration: 3 years, with possible extension.Industry Experience: Utilities & Energy.Energie & Wasserversorgung) or Telecommuni... Mehr anzeigen

PhD student – Antibiotic biosensor protein engineering

The Biozentrum, University of BaselBasel, CH

PhD student – Antibiotic biosensor protein engineering.Starting immediately or as per agreement. Mehr anzeigen

PhD in Media Psychology with a focus on AI chatbot use and social relationships

The Biozentrum, University of BaselBasel, CH

Coordinate and manage the two-wave panel study of the collaborative project.Collaborate with the project partners in Karlsruhe and Zürich to write project reports.Conceptualize, design, conduct, an... Mehr anzeigen

Global Innovation Scientist – DP & Bridging Technologies m/f/d

CordenPharma International Switzerland LLCBasel

CordenPharma is a leading full-service Contract Development and Manufacturing Organization (CDMO) specializing in active pharmaceutical ingredients (APIs), excipients, drug products (DP), and packa... Mehr anzeigen

Scientific Data Architect - Basel, Switzerland

TetraScienceBasel, BS, CH
Quick Apply

TetraScience is the Scientific Data and AI Company building Tetra OS, the operating system for scientific intelligence.We help the world’s leading life sciences firms turn fragmented scientific dat... Mehr anzeigen

Junior Product Manager Neuroimmunology

BÜHLMANN Laboratories AGSchönenbuch, CH

Junior Product Manager Neuroimmunology.Shape the future of diagnostics – join our leadership team!.BÜHLMANN Laboratories AG is an internationally active and growing life sciences company headquarte... Mehr anzeigen

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QC Senior Project Expert Team Lead

Cpl Life SciencesSwitzerland, Basel City, Europe

Our client is looking for an experienced QC Team Lead to join a successful CDMO branch, located in Basel, Switzerland.This role is open to EU citizens willing to relocate to Switzerland (relocation... Mehr anzeigen

Senior Statistical Methodology Data Scientist

Genentech, IncBasel

This role is in the Statistical Methodology group, a core function within Product Development Data Sciences (PDD) that strives to enable the most impactful use of quantitative methodology at Roche ... Mehr anzeigen

Head of Student & Postdoc Affairs (80 -100%)

Friedrich Miescher InstituteBasel, BS, CH

Due to an upcoming retirement, we are seeking a .In this pivotal role, you will serve as a liaison between PhD students, postdocs, and faculty, fostering a supportive and productive research enviro... Mehr anzeigen

Leitung Bildung Pflege

Felix Platter-SpitalBasel, CH

Mit über 1000 Mitarbeitenden zählt die Universitäre Altersmedizin FELIX PLATTER zu den führenden Institutionen der Schweiz für Altersmedizin, Psychiatrie und Rehabilitation.Bei uns verbinden sich h... Mehr anzeigen

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Forum Basiliense Junior Fellows

The Biozentrum, University of BaselBasel, CH

We invite fellows for visits of three to six months during 2027, preferably during the spring or the autumn term.Fellows are expected to participate in events and in scientific exchange (a regular ... Mehr anzeigen

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Research Associate, Mitochondrial Therapy Translational Research

Research Associate, Mitochondrial Therapy Translational Research

The Biozentrum, University of BaselBasel, CH
Vor 13 Tagen
Stellenbeschreibung

Your position

  • Design and execute genome-wide CRISPR knockout, CRISPRa, and CRISPRi screens in mammalian cell models
  • Validate screening hits using arrayed CRISPR experiments and orthogonal func-tional assays in relevant disease models
  • Establish, optimize, and routinely perform cell-line generation workflows using mito-chondrial transfer in immortalized and primary cells
  • Generate and analyze NGS and RNA-seq data from primary tissues and cultured cells
  • Develop and optimize cell-type-targeted mitochondrial transfer approaches in rele-vant in vitro and ex vivo models
  • Independently design, perform, document, and interpret experiments in a rigorous and reproducible manner
  • Work closely with technical staff and help supervise research assistants while re-maining experimentally active
  • Contribute experimentally to translational documentation, regulatory preparation, and clinical protocol development
  • Present experimental results internally, to collaborators, and at international confer-ences
  • Mentor junior lab members through direct experimental guidance and training

Your profile

  • PhD in biology, cell biology, molecular medicine, or a related field
  • Strong hands-on experience with CRISPR-based screening and NGS analysis
  • Solid background in cell culture, molecular biology, and in vitro functional assays
  • Experience with recombinant protein production
  • Experience with RNA sequencing is desirable
  • Demonstrated ability to work independently and manage large-scale, multi-step ex-periments
  • Experience working under BSL-2 conditions
  • Excellent organizational skills and strong attention to experimental detail
  • Clear scientific communication skills and a collaborative working style