ERP Systems Manager

Do you have hands-on experience owning financial ERP systems? Are you excited about being the owner and strategic lead for a key system at the heart of operations at a growing health tech company?

If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS IT/Finance Team as a ERP Systems Manager, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.

This role is a hybrid opportunity, requiring 3 days onsite our corporate office in Bidart, FR, Rolle, CH or Boston, MA.

Our Mission

We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.

Your Mission

As a Financial Systems Manager, you will primarily act as the functional and operational owner of our ERP system (Microsoft Dynamics 365). This position will drive operational improvements and automation initiatives across Finance and Operations.

This role will be the key liaison between business teams and external consultants, ensuring ensuring our ERP ecosystem evolves to meet changing business needs, regulatory requirements, improved efficiency and industry best practices.

The ideal candidate is both strategic and hands-on — a D365 super user who understands finance and supply chain processes, can manage priorities, and occasionally dive into integration or configuration work directly. This role requires a blend of business acumen, technical expertise, and leadership to maximize the value of our ERP investment.

The value you add:

• Serve as the primary functional owner of the ERP (Dynamics 365 Finance & Operations)
• Lead process improvement initiatives across Finance and Supply Chain
• Act as the main point of contact for ERP System Integrator, other consultants and manage the relationship effectively
• Prioritize and coordinate change requests, enhancements, and support tickets
• Own user management, licensing, and role-based access controls within the ERP
• Functional owner for SOX ITGCs related to the ERP responding to request from internal and external auditors, support Head of SOX in the implementation of segregation of duties (SoD) and internal control improvements
• Be the central contact for all ERP integration projects between financial and non-financial systems (CRM, AP tools, etc.)
• Perform or assist with technical integration and data mapping directly
• Collaborate closely with Finance, Supply Chain, and IT teams to ensure ERP alignment with business processes
• Lead acceptance testing, training, and documentation of new functionalities and additional financial systems

Requirements

• Bachelor’s or Master’s degree in Finance, Information Systems, Business Administration, or related field
• Proven experience as an ERP functional owner, ERP manager, or super user (preferably Microsoft Dynamics 365 Finance & Operation)
• Strong understanding of finance and supply chain processes
• Experience managing external ERP consultants and prioritizing support or development requests
• Knowledge of user management, licensing, and role-based access controls
• Familiarity with segregation of duties (SoD) principles
• Experience with system integrations (APIs, data flows, connectors) — hands-on skills a plus
• Excellent communication and coordination skills across business and technical teams
• Fluent in English (French is an asset)

Benefits

You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.

Business recognition and accolades include:

• World's most innovative companies (Top 10)
• World's smartest companies (Top 50)
• 100 Best Places to Work in Boston
• Top 10 European Tech Startup
• Top 10 European biotechs startup to watch
• Top 25 East-Coast Biotech to watch

Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:

• Sickness and Accident coverage through Helsana
• Meal Vouchers at 90CHF PM with our partner cafeteria
• A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit/snacks
• Free parking in an easy to access location
• A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
• As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally

Our DNA

Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous

Our Virtues

At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.

At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal

The Process

We use the power of AI to help our partners make decisions. If you’re utilising AI in your search and application process, why not use some of these prompts, or read our AI guide.

‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’

‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’

‘I am a *job title* - What can SOPHiA GENETICS offer my career?’

Apply now with your CV and any supporting information.

Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance.

We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please.

Starting Date: Jan 2026

Location: Bidart, Nouvelle-Aquitaine, FR or Rolle, CH or Boston, MA

Contract: Permanent

MA Pay Range: USD 88'000-168'000

Disclaimer: The estimated pay range represents a good faith estimate of what the Company expects to pay a successful applicant for the listed position and applies specifically to candidates based in Massachusetts. Due to various factors, the estimated pay range may vary in other locations. Should the level or location of the role change during the hiring process, the applicable base range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, job related skills, years of experience, location, relevant education or training, internal equity, and alignment with market data. The range does not include benefits, and if applicable, bonus, commission, or equity.​