Preclinical PK / PD Modeler / Quantitative Pharmacology Scientist

Ridgeline Discovery , a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of >

50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale.

To strengthen our Preclinical development team, we are seeking a Preclinical PK / PD Modeler . This role is well suited for a (senior / principal) scientist with a strong experimental life‑sciences background who has developed solid expertise in preclinical PK / PD modeling and enjoys close collaboration with research teams.

The position will support both small‑ and large‑molecule programs  across therapeutic areas and will involve the design, coordination, interpretation, and communication of in vivo pharmacology studies .

RESPONSIBILITIES

• Develop and apply PK / PD models for small and large molecules
• Establish and refine in vitro-in vivo correlations (IVIVC) and integrate in vitro data in translational PK / PD strategies
• Develop human PK / PD and exposure predictions, including first‑in‑human dose estimations and early translational modeling to support clinical study planning
• Support programs at early research, helping to inform compound design, optimization strategies, compound selection and support the definition of target product profiles
• Design, coordinate, oversee, analyze, and interpret in vivo pharmacology studies using population‑based modeling approaches
• Work closely with internal team members and CROs to ensure studies are fit for purpose, model‑informed, and aligned with project goals and strategy
• Act as a quantitative scientist within cross‑functional project teams
• Communicate modeling results and recommendations clearly to other scientists and stakeholders
• Contribute to internal reports, data management, project documentation, and, where appropriate, external presentations or publications
• Mentor scientists and help shape best practices in quantitative pharmacology

QUALIFICATIONS

QUALIFICATIONS

WHAT WE CURRENTLY OFFER

To apply , please submit your completed application form along with your CV, cover letter, and reference letters .