Senior Scientist, Biomarker Development

Ready to shape the future of precision medicine by developing cutting-edge biomarker assays that accelerate smarter clinical decisions and improve patient outcomes?

Proclinical is seeking a Senior Scientist specializing in Biomarker Development to join a dynamic team in Switzerland. In this hands-on, laboratory-based role, you will focus on developing and validating state-of-the-art biomarker assays to support clinical programs. Collaborating with global experts, you will contribute to the implementation of innovative biomarker technologies, enabling smarter decision-making and improved patient outcomes.

Please note that to be considered for this role you must have the right to work in this location or hold an EU passport.

Responsibilities:

• Develop and validate soluble biomarker assays, with a focus on ligand binding assays such as ELISA, MSD, NULISA, and Ella, as well as advanced technologies like LC-MS.
• Provide expertise in transferring, implementing, and monitoring biomarker assay development, validation, and sample analysis at external providers.
• Generate and interpret biomarker assay data to support proof of mechanism, dose selection, and proof of biology in early clinical programs.
• Present results at internal meetings and ensure the quality and timely delivery of data from both internal and outsourced activities.
• Serve as the scientific and technical lead for exploratory soluble biomarker assays, including strategy, data quality, interpretation, documentation, and alignment with clinical study endpoints.
• Maintain high standards for scientific rigor, data integrity, compliance, safety, and technical excellence.

Key Skills and Requirements:

• Degree in Biology, Immunology, Cell Biology, or a related field, with relevant laboratory experience.
• Strong expertise in ligand binding assays; experience with LC-MS methods and related technologies is a plus.
• Analytical thinking, accountability, and collaborative teamwork skills.
• Familiarity with regulatory requirements relevant to biomarker development (e.g., GCLP, ICH).
• Proficiency in software tools such as Excel, Word, PowerPoint, SoftMax Pro, SMART Book, GraphPad Prism, and Watson LIMS.
• Strong written and verbal communication skills.
• Experience working in a global organization or matrix-resourcing model is advantageous.
• Applicants must hold an EU/EFTA or Swiss passport or have an unrestricted Swiss residence/work permit.