StellenbeschreibungppResearch Associate - - coagulation / LTK1 / in vitro assays / taking blood / English /p pbProject /b: For our customer a big pharmaceutical company in Basel we are looking for a highly qualified Research Associate for in vivo Nonmalignant Hematology Research /p pbBackground /b: We are seeking a Research Associate to support the preclinical evaluation of novel therapies for nonmalignant hematologic disorders, including bleeding and thrombotic diseases and anemia. Working within a multidisciplinary team, you will assess efficacy, safety, and translational relevance using complementary in vivo and ex vivo approaches with preclinical animal models and human blood and plasma samples. While this role is sitting in the Discovery unit, we work very closely together with clinical teams. Hence, the role requires end-to-end experimental ownership, including hands-on animal studies, sample collection and processing, execution of functional assays, data analysis, and characterization of drug candidates in hemostasis and thrombosis. /p pbThe perfect candidate /b: MSc/BSc in Life Sciences or completed apprenticeship with hands‑on study experience, an active LTK1 (or FELASA equivalent) certification and proven experience in rodent work, including intravenous injections and blood collection. The LTK certification would ideally be current, with all required continuing‑education obligations completed at the time of starting the position, allowing the candidate to perform animal work immediately. Experience in molecular and biochemical assays, coagulation biology and industrial research settings is strongly preferred, along with strong organizational skills, fluency in English and a proactive, team‑oriented mindset. /p pbTasks Responsibilities /b /p ul liDesign, execute and analyze diverse in vivo and in vitro experiments in the field of coagulation /li liDemonstrated hands‑on experience with rodent work, including intravenous injections and blood collection /li liCharacterize efficacy and safety of novel pharmaceutical assets using molecular and biochemical assays (e.g., ELISA, thrombin generation assay, chromogenic assays) in murine and human samples /li liPrepare, handle, and test patient‑derived material (blood and plasma) in in vitro and ex vivo settings /li liPerform data analysis and present results within the team /li liMaintain thorough documentation and contribute to general lab organization, safety, and inventory management /li /ul pbMust Haves /b /p ul liMSc or BSc in Life Sciences (e.g., molecular biology, pharmacology, immunology,coagulation) with at least 2-3 years hands‑on animal study experience (No PhD accepted) /li liOr, completed an apprenticeship as Research Associate ("Lehrabschluss") with at least 4-5 years of academic or industry experience. /li liActive LTK1 certification, FELASA certification, or equivalent, ideally with current mandatory continuing‑education requirements already fulfilled /li liStrong hands‑on in vivo skills including compound administration, monitoring and organ sampling /li liStrong hands‑on experience of in vitro assays, including but not limited to DNA/RNA isolation, ELISA, qPCR, biochemical assays and protein‑based assays /li liStrong experience and independence in experimental design and data analysis /li liAbility to independently execute and manage in vivo and in vitro studies from start to finish /li liFluency in English /li /ul pbNice to Have /b /p ul liHands‑on experience with thrombin generation and chromogenic substrate assays /li liExperience performing surgical procedures in rodents, such as in vivo thrombosis assays and in vivo bleeding models. /li liKnowledge of coagulation, hemostasis, bleeding, or thrombosis biology /li liPrior pharmaceutical or biotechnology industry experience /li /ul pbReference Nr.: /b SDAbr/bRole: /b Research Associate - vivo Nonmalignant Hematologybr/bIndustrie: /b Pharmabr/bWorkplace: /b Baselbr/bPensum: /b 100%br/bStart: /b br/bDuration: /b 12++br/bDeadline: /b /p pbAbout us /b: ITech Consult is an ISO 9001:2015 certified Swiss company with offices in Germany and Ireland. ITech Consult specialises in the placement of highly qualified candidates for recruitment in the fields of IT, Life Science Engineering. /p /p #J-18808-Ljbffr