Translational Medicine Expert – Dermatology, Associate Director

ph3Job Summary /h3pAs a Translational Medicine Expert (TME) you will provide medical and scientific expertise and leadership to: /pulliDrive success of early global programs, develop and implement strategies to achieve Transition Decision Point (TDP). /liliDrive success of late global programs by developing and implementing strategies that lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. /liliSupport Translational Research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. /liliProvide scientific expert assessments and support for in‑licensing opportunities, including due diligences. /li /ulh3Key Responsibilities /h3ulliEarly clinical projects (Phase I/II, "Discovery"): Develop, in collaboration with the dermatology therapeutic area and work with teams to carry out strategies for the Translational Medicine component of drug development projects from research to TDP in single or multiple indications, including post‑indication expansion (PIE) projects. /liliLate‑stage clinical projects (post‑TDP, "Profiling"): Act as a key leader in developing the Phase 2‑3 and post‑approval profiling strategy for drug programs, representing TMDP on the Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized to support pivotal trials, such as special populations, drug‑drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc. /liliTranslational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with the dermatology TA Head, BR research scientists, and other TM line functions (BMD, CSI, PCS, PKS), develop strategies to identify initial or expansion (PIE) indications, and to obtain sufficient evidence to fund these ideas. /liliBusiness Development and Licensing (BDL; in‑licensing and out‑licensing compounds): Participate on BDL teams as the TM representative. /liliGeneral responsibilities: Responsible for clinical monitoring and integrated safety data review during and after the live phase of a study. Provides medical and scientific leadership and expertise to all line functions on the study team. Represent clinical Translational Medicine aspects to Health Authorities and other stakeholders (e.g., payers, patient advocacy groups). Oversee publication strategy for TM studies; lead writing of scientific publications; present study results externally where appropriate. /liliLeadership: Lead study‑specific teams/clinical trial teams in partnership with other line functions. Lead BR‑sub‑team(s) on Global Project Teams for late‑phase programs. Collaborate closely with other TM (especially CSI) and non‑TM (especially Project Management) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific standards and innovation. /li /ulh3Essential Requirements /h3ulliDoctoral degree, MD Board‑certified Dermatologist; preferably Ph.D. within dermatology/immunology. /liliAt least 5 years of experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. /liliInnovation: Seeks out new clinical discovery opportunities and approaches to reach TDP. /liliRecognized expert in the field, driving success for individual studies and projects; respected by colleagues across RD, Development, and externally. /liliFluent oral and written English. /li /ulh3Benefits Rewards /h3pAt Novartis, we’re committed to reimagining medicine together – and rewarding the people who make it happen. Expected Annual Base Salary Range for role: 122,500.00 – 227,500.00 CHF. The base salary is determined based on gender‑neutral objectives such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and will be reviewed periodically upon joining Novartis. /ppIn addition to the base salary, you may be eligible for a performance‑based bonus depending on certain performance parameters. The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and a minimum 14 weeks paid parental leave. Long‑term equity awards granted at group level may also be part of your package. Pay equity is a fundamental principle of our employment policy and reflects our commitment to creating a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics. /ph3Commitment to Diversity and Inclusion / EEO /h3pNovartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. We are an equal opportunity employer and do not discriminate on the basis of race, colour, religion, gender, sexual orientation, gender identity, age, national origin, ancestry, disability, genetic information or other protected characteristics, as defined by applicable law. /ph3Accessibility and Accommodation /h3pNovartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please contact us. Please note you do not need to include the job requisition number in your message. /p /p #J-18808-Ljbffr