Senior Expert Science & Technology Upstream Process Modeling & Simulation

Job Description Summary

Location: Basel Switzerland #onsite

Role Purpose:
We are looking for a scientist with a strong background in Data Sciences Modeling & Simulation and AI applications to support and advance our upstream bioprocess development efforts. This role is ideal for a technically skilled and passionate individual who thrives at the intersection of biotechnology and data science.
The position may be appointed at either the Senior Expert or Expert level depending on the candidates experience and seniority.

Job Description

Your responsibilities include but are not limited to:

• Design develop and deploy advanced modeling and simulation strategies for upstream cell culture processes including:
  • Mechanistic data-driven and hybrid models
  • In silico process optimization and scenario analysis
  • Digital Twins with integration of Model Predictive Control (MPC) and Process Analytical Technology (PAT)
• Identify and implement solutions incl. generative AI (genAI) to extract and process data from structured and unstructured sources (e.g. ELNs LIMS scientific publications) and to derive bioprocess insights.
• Collaborate with global stakeholders and peers to align modeling strategies share best practices and contribute to the development of modeling standards and platforms.
• Support cross-functional digitalization initiatives within the global Upstream Process Development network including data infrastructure and digital workflows.
• Train peer scientists on modelling tools and solutions for streamlined upstream process development
• Ensure compliance with data integrity quality and regulatory standards in all modeling and digitalization activities.

What youll bring to the role:

• Education / Experience:
  • MSc in Biotechnology Biochemical Engineering Bioinformatics Data Science Mathematics or similar with a strong background in (bio-)process modelling (mechanistic data-driven and hybrid models) or data analytical methods in the field of bioprocessing. Relevant professional experiencein process modeling and digitalization.
• Technical Expertise:
  • Demonstrated experience in data analytics and/or modeling & simulation of industrial cell culture processes.
  • Demonstratedprogramming skills (R Python or MATLAB) and knowledge ofMachine Learning algorithms.
  • Deep knowledge in one or more of the following areas:
    • Machine learning and data analytical methods
    • Mechanistic modeling (e.g. mass balances kinetic models or hybrid modelling)
    • Digital twin development and real-time process control
  • Experience withgenerative AI(e.g. LLMs diffusion models) for knowledge extraction process design or automation is a strong plus.
  • Proficiency in relevant modelling tools and platforms e.g:
    • Programming languages: Python R MATLAB
    • Modeling software: gPROMS Aspen Plus Simulink
    • AI/ML frameworks: TensorFlow PyTorch scikit-learn
  • Understanding of bioprocessing principles and unit operations is advantageous.

• Languages:
  • Fluency in English oral and written; German is a plus.

Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If because of a medical condition or disability you need a reasonable accommodation for any part of the recruitment process or in order to receive more detailed information about the essential functions of a position please send an e-mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Skills Desired

Required Experience:

Senior IC

Key Skills
Hr Executive Recruitment,Internship,AIX,Fleet,Information Technology Sales
Employment Type : Full-Time
Experience: years
Vacancy: 1