Technical R&D Associate Scientist (m / w / d)

Technical R&D Associate Scientist (m / w / d)- analytical instrumentation / HPLC / MS / LC-MS / oligonucleotides / English

Project :

For our pharmaceutical customer based in Basel, we are looking for a Technical R&D Associate Scientist (m / w / d)

Background :

Behind each product in clinical trials or sold by Roche is the involvement of Pharma Global Technical Operations. Pharma Global Technical Operations makes medicines with more than 10’000 employees at sites around the world. „Pharma Technical Development“ is a global organization with over two thousand people dedicated to the development of new medicines to meet patients‘ needs. We actively collaborate and develop creative technical solutions to expertly deliver the pipeline and supply high quality products to patients. The group excels in its work through innovation, teamwork, dedication, and mutual respect and contributes every single day to bring new therapies to life and hope to patients. „Synthetic Molecules Technical Development“ (PTDC) brings a broad range of experience across drug substance, drug product, and analytical sciences, and collaborates closely with partners in research and early development, Pharma Technical Development, and Commercial. PTDC is responsible for the technical development of our synthetic molecules pipeline and the manufacture of clinical supplies for clinical studies. The position on offer is located in Analytical Research and Development for Synthetic molecules within Pharma Technical Development. Analytical Development for synthetic molecules is responsible for the development of resource and cost-efficient analytical methods by use of state of the art and innovative techniques such as high-performance liquid chromatography, gas or ion chromatography or mass spectrometry. The ultimate goal of our work is the development of a robust control strategy to release products for clinical trials, and finally for commercial supply.

The perfect candidate : Has completed a vocational scientific qualification (e.g. apprenticeship)or holds a Bachelor’s / Master’s degree and brings 3-5 years of experience in the pharmaceutical industry with a clear focus on analytical development for oligonucleotides. They offer strong hands-on expertise with HPLC, MS and ideally LC-MS, an excellent quality mindset with great attention to detail, and the ability to quickly adapt to new tools, ideas and agile ways of working while communicating confidently in English.

Tasks & Responsibilities :

• Development, improvement and validation of analytical methods for the quality assessment of starting materials, intermediates, reaction monitoring, active substances and galenical forms
• Thorough and efficient planning, execution and documentation of experiments in collaboration with the relevant team members, analytical project lead and your supervisor, following current GxP guidelines as well as relevant SOPs
• Work on end-to-end processes in close collaboration with other associate scientists, scientists, and partners from other departments to ensure efficient analytics and continuous improvement
• Coordination of analytical activities, including sample management for the development of synthetic products
• Authoring of documents, e.g., analytical procedures, validation reports, user manuals, SOPs

Must Haves :