Research Associate

The Position

In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines.

Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

You will join Roche’s Institute of Human Biology (IHB), an organization within pRED whose goal is to harness and advance the use of human model systems in drug discovery and development, as well as personalized medicine. Our interdisciplinary research bridges academic and pharmaceutical research, connecting biologists, engineers, and data scientists. We partner and collaborate with leading scientific institutions worldwide to tackle grand challenges by assembling, funding, and leading interdisciplinary teams of experts to work on highly ambitious and complex scientific questions.

Role Mission

In close collaboration with the Neurosciences and Rare Disease (NRD) Discovery Translation Area within pRED, we are looking for an independent and highly motivated research associate to join our team at the interface of academic and translational research. The research associate will play a key role in characterizing iPSC-derived cell types of the central nervous system with Alzheimer’s disease-related mutations. Our vision is to establish foundational in vitro technology for drug profiling by synergizing with the unparalleled expertise at the IHB to investigate poorly understood clinical findings and address the needs of the future NRD portfolio.

Your Impact

Characterize iPSC- and fibroblast-based models of Alzheimer’s disease

Contribute to the generation of new iPSC models with CRISPR engineering

Maintain stem cell and primary cell cultures

Support the development of in vitro assays

Rigorously document protocols and experimental results

Present data at internal meetings

Your Profile

MSc with several years of experience in stem cell research or recent PhD graduates.

Hands-on expertise on stem-cell derived models of human brain cell types, biochemistry, molecular biology, immunohistochemistry and basic microscopy

Experience working with CRISPR engineering of mammalian cell lines in a BSL2 environment

You have demonstrated the ability to navigate in a matrix environment to effectively influence, advise, or consult experts to jointly move projects forward

You have a strong work ethic, communication skills and team-player oriented personality

You are fluent in English

Temporary position for 2 years.

Reporting line to : Lynette Foo, NRD

Our commitment

Roche commits to recognising talent and aptitude. We prioritize encouraging and supporting our employees in their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.