Job description
Roles & Responsibilities
- Lead in vitro assay development
- Identify and investigate PD biomarkers relavent to disease and drug intervention
- Develop & design experiments and research plans to elucidate therapeutic mechanism of action
- Conduct and troubleshoot a wide range of biological / molecular / biochemical assays including, but not limited to : FACS, ELISAs, , RT-PCR, Western blotting, co-IPs
- Manage / participate in CRO relationships
- Mentoring of junior colleagues
- Document, analyze, interpret and present experimental data in a clear and concise manner, contributing to data room and investor presentations
- Independently research new technologies and approaches to apply to the drug discovery and development pipeline
- Present in high level conferences, draft and submit manuscripts, contribute to grant writing
In daily practice…..
Setting up the lab and best practicesPlan and Design experiments coordinating with clear milestones on the projectPerform validation assays and preclinical experimentsPerform data analysis and prepare and present reportsDrive CRO interaction and vendor management for preclinical studiesOrganize laboratory, develop SOPs, maintain equipment, order supplies, maintain detailed records of laboratory experiments, and other duties as requiredProfile
Required Qualifications
PhD with 3-8 years of recent lab-based biotech / pharma industry experienceExperience with human (and mouse) biomarkersExperience with protein assay platforms (ELISA, Luminex, MSD, etc.)Experience with flow cytometry methods and interpretation (immunophenotyping, cell markers)Experience and ability to plan and execute molecular, cellular and biochemical techniques in 96 / well formatAble to take direction but also work independently and troubleshootDemonstrates attention to detail and record keepingTeam player : understands and appreciates working towards common goals in start-up environment and in a small teamFlexibility to adapt workplans to rapidly changing priorities and deadlinesCandidates must possess a valid work permit in SwitzerlandPreferred Qualifications
Background in fibrosis, immunology / inflammation, cytokines, growth factors, extracellular matrix biologyKnowledge / experience working with biotherapeutics, mix modalitiesExperience with phenotypic assay development (flow cytometry and microscopy)Experience in high throughput screening such as by phenotype, microscopy, ELISAExperience with IHCWorkplace
Workplace
We offer
Company mission that aims to impact the lives of patients with life threatening conditions with a novel & innovative approachAn opportunity to work in the exciting field of mechno-medicine and its broad implications in fibrosis & oncologyFast-paced, highly stimulating environment with a collaborative atmosphereUnique opportunity to join a company at an early stage, with avenues for career developmentCompetitive salary, with additional advantages and incentives including a fully-funded pensionRespectful and equal opportunity work environment, in a world-class locationTANDEM strives to build a diverse team, and particularly encourages women and other groups underrepresented in the Biotech / Bioengineering field to apply. Submit your detailed CV and a motivation letter for this position by August 10, . Interviews will be scheduled on a rolling basis.
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We look forward to receiving your online application with the following documents :
Motivation letterCVDiplomas and reference lettersPlease note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
Questions regarding the position should be directed to Dr. Mamta Chabria, email (no applications).
For recruitment services the GTC of ETH Zurich apply.
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