Scientist / Senior Scientist

Job description

Roles & Responsibilities

• Lead in vitro assay development
• Identify and investigate PD biomarkers relavent to disease and drug intervention
• Develop & design experiments and research plans to elucidate therapeutic mechanism of action
• Conduct and troubleshoot a wide range of biological/molecular/biochemical assays including, but not limited to: FACS, ELISAs, , RT-PCR, Western blotting, co-IPs
• Manage/participate in CRO relationships
• Mentoring of junior colleagues
• Document, analyze, interpret and present experimental data in a clear and concise manner, contributing to data room and investor presentations
• Independently research new technologies and approaches to apply to the drug discovery and development pipeline
• Present in high level conferences, draft and submit manuscripts, contribute to grant writing

In daily practice…..

• Setting up the lab and best practices
• Plan and Design experiments coordinating with clear milestones on the project
• Perform validation assays and preclinical experiments
• Perform data analysis and prepare and present reports
• Drive CRO interaction and vendor management for preclinical studies
• Organize laboratory, develop SOPs, maintain equipment, order supplies, maintain detailed records of laboratory experiments, and other duties as required

Profile

Required Qualifications

• PhD with 3-8 years of recent lab-based biotech/pharma industry experience
• Experience with human (and mouse) biomarkers
• Experience with protein assay platforms (ELISA, Luminex, MSD, etc.)
• Experience with flow cytometry methods and interpretation (immunophenotyping, cell markers)
• Experience and ability to plan and execute molecular, cellular and biochemical techniques in 96/ well format
• Able to take direction but also work independently and troubleshoot
• Demonstrates attention to detail and record keeping
• Team player: understands and appreciates working towards common goals in start-up environment and in a small team
• Flexibility to adapt workplans to rapidly changing priorities and deadlines
• Candidates must possess a valid work permit in Switzerland

Preferred Qualifications

• Background in fibrosis, immunology/inflammation, cytokines, growth factors, extracellular matrix biology
• Knowledge/experience working with biotherapeutics, mix modalities
• Experience with phenotypic assay development (flow cytometry and microscopy)
• Experience in high throughput screening such as by phenotype, microscopy, ELISA
• Experience with IHC

Workplace

Workplace

We offer

• Company mission that aims to impact the lives of patients with life threatening conditions with a novel & innovative approach
• An opportunity to work in the exciting field of mechno-medicine and its broad implications in fibrosis & oncology
• Fast-paced, highly stimulating environment with a collaborative atmosphere
• Unique opportunity to join a company at an early stage, with avenues for career development
• Competitive salary, with additional advantages and incentives including a fully-funded pension
• Respectful and equal opportunity work environment, in a world-class location

TANDEM strives to build a diverse team, and particularly encourages women and other groups underrepresented in the Biotech/Bioengineering field to apply. Submit your detailed CV and a motivation letter for this position by August 10, . Interviews will be scheduled on a rolling basis.

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We value diversity

In line with to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

Curious? So are we.

We look forward to receiving your online application with the following documents:

• Motivation letter
• CV
• Diplomas and reference letters

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Questions regarding the position should be directed to Dr. Mamta Chabria, email (no applications).

For recruitment services the GTC of ETH Zurich apply.

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