Clinical research associate Jobs in Bülach

Materials science and technology are our passion. With our cutting-edge research, Empa's around 1,100 employees make essential contributions to the well-being of society for a future worth living. Empa is a research institution of the ETH Domain

The PhD research will be entailing an international recurrence case study and focuses on applying and optimizing 3D X-ray virtual histology methods by micro-CT for recurring thyroid tumors. The acquired and already existing database will be used to further develop ML models for the automated detection of clinically relevant markers. The goal is to develop the technique towards potential clinical use to enable precision medicine diagnostics for the patient and couple it with high-field MRI imaging to extend towards in-vivo applications. The project is interdisciplinary and the PhD student will work in close collaboration researchers and clinical experts from the University of Bern. Your contribution :  Application and further development of 3D virtual histopathology by X-ray phase contrast micro-CT for recurring thyroid carcinoma cases using FFPE blocks Further development of ML tools and models for the automated detection of clinically relevant morphological features for the diagnostics of such tumors Establishment of a unique 3D micro-CT histology data base for recurrent thyroid carcinomas Data management, data treatment Extension and coupling with high-field MRI technology towards in-vivo diagnostics Your profile

You would like to make a major impact on personalized medicine of thyroid carcinomas, 3D cancer diagnostic and revolutionize digital pathology, you are highly motivated, communicative and passionate working in an interdisciplinary field and fulfill the following criteria :

• Completed Master's degree in biomedical engineering, physics or similar
• Have strong hands-on lab skills
• Have some experience with X-ray methods and imaging
• Have preferably some additional experience in the biomedical domain and / or in image processing
• Have preferably some experience using ML models and tools (e.g. radiomics) in image processing and in programming (Python, C, Matlab etc.)
• Fluent in English, German is beneficial

We offer an international, highly stimulating research environment with excellent infrastructure and broad interdisciplinary surroundings with plenty of possibilities for personal and professional development. The project duration is three years with the potential extension by one more year. Desired starting date is as soon as reasonably possible or upon mutual agreement.